Aesthetic Medicine: All About Collagen and Hyaluronic Acid Wrinkle Fillers There are many

Filling wrinkles: the first injections

The first injections for filling wrinkles date back twenty years. The principle of filling wrinkles: spread in the tissues of American collagen, under two different densities, Zyderm and Zyplast. Of bovine origin, it requires two preliminary tests, fifteen days apart, to ensure that it does not cause any reaction. But after the mad cow crisis, collagen has fallen into disuse for the benefit of hyaluronic acid for the filling of wrinkles. The latter (Restylane, Juvederm or Surgiderm), non-animal and obtained by biotechnology, is also injected into the syringe, but immediately without testing.

Filling wrinkles: collagen, for or against

For the filling of wrinkles, collagen and hyaluronic acid are resorbable implants with a limited life span. They are degraded by the body and allow a "backtracking". Today, collagen is trying to regain the market of aesthetic medicine and filling wrinkles with formulas that dispense with tests. Despite this technical performance, the opinions of the doctors diverge. "Unconditional hyaluronic acid, however, I recognize that the new collagens have some interest to polish, refine and perfect a rejuvenation treatment, says Dr. Marie-Thérèse Bousquet, aesthetic doctor. Especially to coat the top of the upper lip and fill the fine lines without thickening, inflating or rolling. The studies carried out by Inamed laboratories on the new Cosmoderm and Cosmoplast collagens, injectable without prior tests, have so far not shown any inflammatory reaction. "
This opinion is not shared by Dr. Laurent Mirallès, who also specializes in anti-aging injections. "I have long since abandoned Zyderm and Zyplast collagen. Although they are excellent products, they seem to me outdated today. Indeed, they always require two preliminary tests to check if they are well tolerated. You will understand why I do not want to take a risk, as minimal as it is, to inject other forms of collagen type Evolence, Cosmoderm or Cosmoplast. We still need to step back to be certain that these products do not provoke any delayed reaction. In a year or two, we can talk about it again. "

Wrinkle Filling: Hyaluronic Acid

Its success, it owes it both to its maneuverability (it is easy and quick to inject) and to the better durability of its results (from eight to twelve months depending on the areas injected and individuals, according to specialists). And his family is growing: filling wrinkles, facial remodeling, mesotherapy ... it is used in various densities to respond more accurately to each area and each type of injection. Top of the top for lips, Restylane Lip allows more fluidity and mobility of the mouth, with a more natural result, and Surgiderm Surgilips, which globally treats the signs of aging. "On average, says Dr. Ghislaine Beilin, aesthetic doctor, hyaluronic acid is almost six months in the lips because they are hyper-vascularized, highly mobile and poorly protected against thermal shock." These new very specific acids repulpate, rewire, but act on the filling of wrinkles and fine lines of the upper lip without inflating it.

Filling wrinkles: namely

The acronym CE only guarantees the safety of manufacture.
The new collagens for filling wrinkles, such as hyaluronic acid, are not free of contraindications: allergies and autoimmune diseases, for example. The practitioner's questionnaire is therefore indispensable.

Filling wrinkles: new collagens

- Of porcine origin, Evolence Collagen was developed by Colbar Lifescience Ltd, an Israeli biotech company specializing in surgical products and tissue engineering. Purified, it has a high immunocompatibility, and is therefore very well tolerated by the human body. Lifetime announced by the laboratory: twelve months in 90% of cases.

- Based on tissue engineering technology, Cosmoderm and Cosmoplast are collagens of human origin, obtained from stem cells of a single donor. Used for fifteen years in the reconstruction of skins of burn victims, this collagen has been the subject of several studies in the field of immunodepression. In aesthetics, it has been used for just a year to fill wrinkles. Lifespan: more than six months. Price: 350 euros approximately the injection.